5 Common Questions About Synthetic Peptides

Synthesized peptides are extensively used in hormonal treatments, anti-bacterial treatments, cosmetic products, and more. A cysteine-containing peptide, for instance, is helpful to increase energy and promote better sleep. Here we have shared answers to frequently asked questions about Cys-containing peptides.

How Should You Store Peptides?

Peptides should be stored in the deep freezer with a temperature of less than -15°C, particularly for long-term storage, because some peptides, such as a cysteine-containing peptide, begin to degrade at room temperature. Peptides, generally, remain potent for several weeks when stored at -20°C or -80°C. For short-term storage, +4°C is the best temperature to keep peptides from degrading. It’s best to protect peptides from direct sunlight.

Do peptides dissolve in water?

As peptides have varying solubility properties, some peptides may not readily dissolve in water like others. Peptides that contain hydrophobic or nonpolar residues in a high percentage are generally insoluble in water.

How to keep synthetic peptides in solution?

As dissolved peptides are not stable as their counterparts, that is, dry powder, aliquoting the solution before freezing is crucial to avoid refreezing cycles. Asparagine or Cysteine containing peptides can be less stable due to possible oxidization. It’s best to have stock solutions in dry organic solvents as they prevent premature hydrolysis.

Do cysteine-containing peptides easily oxidized?

Most peptide synthesis companies provide cysteine-containing peptides as monomers. Treatment with dithiothreitol before using the peptide for an experiment is helpful to prevent air oxidation.

How to dissolve free cysteine-containing peptides?

Peptides that contain free cysteine may oxidize and form dimers at pH>7. However, it’s possible to reverse the oxidation. As pH between 7-8 is best for the formation of the disulfide bond; therefore, free cysteine-containing peptides are dissolved in degassed solvents.

If you need peptides containing cysteine for research purposes, you can get in touch with peptide manufacturing companies.

Comments

Post a Comment

Popular posts from this blog

3 Things To Consider Before Purchasing GMP Peptide Synthesis

GMP peptides are commonly used in the pharmaceutical and cosmetic industries. As they have to be used in the formulation of different materials, you need to look at their characteristics before you buy them. Once you are sure of the properties that you look for, you should purchase affordable GMP peptide synthesis from the right places. To help you make an informed decision about buying GMP peptides, here is a list of some of the things that you should look at. 1. Quantity of Order You should start by looking at the quantity of the peptides that you need to order. This means that you should know whether you need to order GMP peptides on a small scale and a large scale. You can convey your requirements and specifications about the peptides to the supplier and get the peptides the way you want. 2. Length of Amino acids  It will help if you knew the length of the amino acids of the peptides that you need. For instance, you can tell the manufacturer to supply GM
Read more

Unraveling The Wonders Of Biotin-Tripeptide A Deep Dive Into A Biochemical Symphony

Image
In the intricate world of biochemistry, certain compounds emerge as silent heroes, playing pivotal roles in various physiological processes. Biotin-tripeptide , a fascinating amalgamation of biotin and a tripeptide structure, stands out as one such biochemical marvel. In this blog, we embark on a journey to explore the wonders of biotin-tripeptide, delving into its structure, functions, and the burgeoning interest it has garnered in scientific circles. Understanding Biotin-Tripeptide: Biotin, also known as Vitamin B7, is a water-soluble vitamin crucial for various metabolic functions in the body. It plays a vital role in converting food into energy and is renowned for its impact on healthy skin, hair, and nails. Tripeptides, on the other hand, are compounds composed of three amino acids linked together by peptide bonds. These amino acids are the building blocks of proteins, which serve as the foundation for numerous biological processes. Biotin-tripeptide is a unique fusion of biotin a
Read more

Custom Peptide Synthesis: Tailoring Molecules for Research and Medicine

Image
In the ever-evolving landscape of biomedical research and drug development, custom peptide synthesis has emerged as a cornerstone technology. This specialized process involves the production of specific peptide sequences tailored to meet the precise specifications of researchers and pharmaceutical developers. Here's an in-depth look at how custom peptide synthesis is revolutionizing the field and what it means for the future of science and medicine. What is Custom Peptide Synthesis? Custom peptide synthesis is the systematic construction of peptide chains according to predetermined sequences. It allows scientists to create peptides with specific amino acid sequences that are not readily available in nature or through generic manufacturing methods. This bespoke approach enables the exploration of protein interactions, the development of new drugs, vaccines, and diagnostics, and aids in the study of complex biochemical processes. The Process of Custom Peptide Synthesis The synthesis
Read more