Why Purity Isn’t the Only Metric That Matters in Custom Peptide Synthesis
When you order a peptide for your research, the first thing you usually notice is the purity number. It might say 95%, 98%, or even 99%. That single number can feel like a promise: “This is high quality.” And yes—purity is important. But if you’ve ever had a peptide behave oddly in an assay, dissolve poorly, or give results that don’t repeat, you already know the truth: purity alone doesn’t guarantee success. Purity is a helpful snapshot, not the full movie. In custom peptide synthesis , real quality comes from a few other checks that quietly decide whether your peptide will perform the way you need it to. What Purity Really Measures Most purity values come from an HPLC test, which separates the components in your sample and shows how much of it looks like the “main” peptide peak. In plain words, it’s checking how much of your vial appears to be the primary peptide compared to smaller byproducts. That’s valuable information—but it doesn’t answer every question a researcher cares a...